DECIPHERING THE ROLE OF AUTOPHAGY IN HEART FAILURE

Deciphering the role of autophagy in heart failure

Heart failure (HF) refers to a progressive pathological condition when cardiac muscles fail to pump adequate blood supply (cardiac output) to meet the metabolic Little Boys Flannel demand of the body.Among various cellular and molecular mechanisms identified for the onset and progression of HF, autophagy dysregulation is increasingly getting recogn

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Data comparing the kinetics of procollagen type I processing by bone morphogenetic protein 1 (BMP-1) with and without procollagen C-proteinase enhancer 1 (PCPE-1)

This article provides kinetic constants for C-terminal processing of procollagen type I by bone morphogenetic protein 1 (BMP-1; the major procollagen C-proteinase), a reaction stimulated Large Door Bookcase by the connective tissue glycoprotein procollagen C-proteinase enhancer 1 (PCPE-1).Reported are Km, Vmax, Kcat and Kcat/Km (catalytic coefficie

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